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grow muscle from stem cells from skin cells

PostPosted: Sat Jan 13, 2018 10:53 am
by everything
http://www.kurzweilai.net/how-to-grow-f ... stem-cells

In the study, the researchers started with human induced pluripotent stem cells. These are cells taken from adult non-muscle tissues, such as skin or blood, and reprogrammed to revert to a primordial state. The pluripotent stem cells are then grown while being flooded with a molecule called Pax7 — which signals the cells to start becoming muscle.

After two to four weeks of 3-D culture, the resulting muscle cells form muscle fibers that contract and react to external stimuli such as electrical pulses and biochemical signals — mimicking neuronal inputs just like native muscle tissue. The researchers also implanted the newly grown muscle fibers into adult mice. The muscles survived and functions for at least three weeks, while progressively integrating into the native tissue through vascularization (growing blood vessels).