by Peacedog on Tue Nov 13, 2018 11:22 am
Endocrine downregulation is an observed phenomena in people who follow a low carbohydrate diet for long periods of time. Oddly, this does not appear to happen in people following a ketogenic diet for long periods of time.
No good studies exist on this either to my knowledge, but it is an anecdotally observed phenomena that has happened often enough that it appears to be an issue. Also keep in mind this does not happen with everyone. Which is why bloodwork is really important and without it you are shooting in the dark. Also keep in mind that some people, usually in the realm of 3-5%, respond really badly to this kind of diet and bloodwork could keep you from killing them.
When a low carbohydrate diet is followed exclusively for a long period of time, usually in excess of six months, thyroid and testosterone levels tend to drop. Usually by about 25-35%. My guess is it is the body's response to long term calorie restriction in an effort to conserve energy, because it thinks it is starving. Also keep in mind that barring the use of some very dangerous thermogenics, and/or surgery, that you can only deplete fat cells, not destroy them, and that fat cells also have an endocrine system function manufacturing certain hormones like leptin, etc. It's why once someone gets fat, they tend to stay that way without a significant intervention.
The work around for this is to have a cheat day one day per week where the body carboloads and burns it off over the next 2-3 days. People have experimented with this and for some as little as one cheat meal per week seems to stave the effect off. Of course, this is where discipline comes in. And usually where the diet goes straight to hell.
And this is where if you have bodyfat level management problems you start to enter the "damned if you do and damned if you don't" territory.
The long term effects of obeseity are well known: cardiovascular disease, stroke, certain forms of cancer, diabetes, etc.
Having depressed hormone levels isn't fun. Craving carbohydrates all the time is not either. But both appear to be better than being obese in the long run. So, until we figure out the binome vis-a-vis carbohydrate metabolism or find a safe way to systemically destory fat cells in the body, we are stuck with work arounds like diet.
As I always remind people, once you have a bodyfat problem nothing we currently have solves the problem. It is also why I want to sucker punch every asshole who claims "diet solves everything/diet is the ultimate form of medicine." Everything is a bandaid dependent upon compliance. If you stop doing it, all of the problems come back/are frequently worse. Diet is not a reparative therapy. It is a management strategy.
And yes, there are tradeoffs. But generally speaking, all of them are better than being obese.
Last edited by
Peacedog on Tue Nov 13, 2018 11:37 am, edited 3 times in total.